Xylobiose

Product Name : XylobioseDescription:Xylobiose (1,4-β-D-Xylobiose; 1,4-D-Xylobiose) is a disaccharide of xylose monomers with a β-1, 4 bond between monomers.CAS: 6860-47-5Molecular Weight:282.24Formula: C10H18O9Chemical Name: (2R,3R,4R)-2,3,5-trihydroxy-4-{oxy}pentanalSmiles : OC(O1OC(O)(O)1O)(O)(O)C=OInChiKey: SQNRKWHRVIAKLP-RSZZQXBVSA-NInChi : InChI=1S/C10H18O9/c11-1-4(13)7(15)6(2-12)19-10-9(17)8(16)5(14)3-18-10/h1,4-10,12-17H,2-3H2/t4-,5+,6+,7+,8-,9+,10-/m0/s1Purity: ≥98%…

Crocetin

Product Name : CrocetinDescription:Crocetin (β-Crocetin), isolated from Crocus sativus, possesses anti-inflammatory, neuroprotective and antioxidant activity.CAS: 25368-09-6Molecular Weight:342.43Formula: C21H26O4Chemical Name: (2E,4E,6E,8E,10E,12E,14E)-16-methoxy-2,6,11,15-tetramethyl-16-oxohexadeca-2,4,6,8,10,12,14-heptaenoic acidSmiles : COC(=O)/C(/C)=C/C=C/C(/C)=C/C=C/C=C(\C)/C=C/C=C(\C)/C(O)=OInChiKey: DGGQUKOLHQXDLV-QTNXRKSWSA-NInChi : InChI=1S/C21H26O4/c1-16(12-8-14-18(3)20(22)23)10-6-7-11-17(2)13-9-15-19(4)21(24)25-5/h6-15H,1-5H3,(H,22,23)/b7-6+,12-8+,13-9+,16-10+,17-11+,18-14+,19-15+Purity: ≥98% (or refer to…

USP7-IN-3

Product Name : USP7-IN-3Description:USP7-IN-3 (Compound 5) is a potent and selective allosteric ubiquitin-specific protease 7 (USP7) inhibitor.CAS: 2202738-42-7Molecular Weight:568.59Formula: C29H31F3N6O3Chemical Name: 3--6-({4-hydroxy-1-piperidin-4-yl}methyl)-2-methyl-2H,6H,7H-pyrazolopyrimidin-7-oneSmiles : CN1N=C2C(N=CN(CC3(O)CCN(CC3)C(=O)C(C3C=CC=CC=3)C(F)(F)F)C2=O)=C1C1C=CC(CN)=CC=1InChiKey: RLPQYKGBXQQARM-JOCHJYFZSA-NInChi : InChI=1S/C29H31F3N6O3/c1-36-26(21-9-7-19(16-33)8-10-21)24-25(35-36)27(40)38(18-34-24)17-28(41)11-13-37(14-12-28)23(39)15-22(29(30,31)32)20-5-3-2-4-6-20/h2-10,18,22,41H,11-17,33H2,1H3/t22-/m1/s1Purity: ≥98% (or refer…

MEK inhibitor

Product Name : MEK inhibitorDescription:MEK inhibitor is a potent MEK inhibitor with antitumor potency.CAS: 334951-92-7Molecular Weight:426.51Formula: C26H26N4O2Chemical Name: 3-phenyl}imino)(phenyl)methyl]-2-hydroxy-N-methyl-1H-indole-6-carboxamideSmiles : CNC(=O)C1=CC2NC(O)=C(C(=NC3=CC(CN(C)C)=CC=C3)C3C=CC=CC=3)C=2C=C1InChiKey: UPICVLXBXZXYIE-ZZIIXHQDSA-NInChi : InChI=1S/C26H26N4O2/c1-27-25(31)19-12-13-21-22(15-19)29-26(32)23(21)24(18-9-5-4-6-10-18)28-20-11-7-8-17(14-20)16-30(2)3/h4-15,29,32H,16H2,1-3H3,(H,27,31)/b28-24+Purity: ≥98% (or refer to the Certificate…

Baimaside

Product Name : BaimasideDescription:Quercetin 3-beta-sophoroside is isolated from the flowers of A. venetum, is an scavengers of superoxide anions.CAS: 18609-17-1Molecular Weight:626.52Formula: C27H30O17Chemical Name: 2-(3,4-dihydroxyphenyl)-3-{oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-5,7-dihydroxy-4H-chromen-4-oneSmiles : OC1C=C2OC(=C(O3O(CO)(O)(O)3O3O(CO)(O)(O)3O)C(=O)C2=C(O)C=1)C1=CC(O)=C(O)C=C1InChiKey: RDUAJIJVNHKTQC-UJECXLDQSA-NInChi : InChI=1S/C27H30O17/c28-6-14-17(34)20(37)22(39)26(41-14)44-25-21(38)18(35)15(7-29)42-27(25)43-24-19(36)16-12(33)4-9(30)5-13(16)40-23(24)8-1-2-10(31)11(32)3-8/h1-5,14-15,17-18,20-22,25-35,37-39H,6-7H2/t14-,15-,17-,18-,20+,21+,22-,25-,26+,27+/m1/s1Purity: ≥98%…

Thiol-C9-PEG5-acid

Product Name : Thiol-C9-PEG5-acidDescription:Thiol-C9-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.CAS: Molecular Weight:452.65Formula: C22H44O7SChemical Name: 27-sulfanyl-4,7,10,13,16-pentaoxaheptacosanoic acidSmiles : OC(=O)CCOCCOCCOCCOCCOCCCCCCCCCCCSInChiKey: SCWOQJXEVJAGMQ-UHFFFAOYSA-NInChi : InChI=1S/C22H44O7S/c23-22(24)10-12-26-14-16-28-18-20-29-19-17-27-15-13-25-11-8-6-4-2-1-3-5-7-9-21-30/h30H,1-21H2,(H,23,24)Purity: ≥98%…

Glycocyamine-d2

Product Name : Glycocyamine-d2Description:Product informationCAS: 1173020-63-7Molecular Weight:119.12Formula: C3H7N3O2Chemical Name: 2-(H)acetic acidSmiles : C()(N=C(N)N)C(O)=OInChiKey: BPMFZUMJYQTVII-DICFDUPASA-NInChi : InChI=1S/C3H7N3O2/c4-3(5)6-1-2(7)8/h1H2,(H,7,8)(H4,4,5,6)/i1D2Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as…

Enecadin

Product Name : EnecadinDescription:Enecadin is a neuroprotective agent extracted from patent US 8623823 B2.CAS: 259525-01-4Molecular Weight:357.46Formula: C21H28FN3OChemical Name: 4-(4-fluorophenyl)-2-methyl-6-{oxy}pyrimidineSmiles : CC1N=C(C=C(N=1)OCCCCCN1CCCCC1)C1C=CC(F)=CC=1InChiKey: SZSHJTJCJOWMHM-UHFFFAOYSA-NInChi : InChI=1S/C21H28FN3O/c1-17-23-20(18-8-10-19(22)11-9-18)16-21(24-17)26-15-7-3-6-14-25-12-4-2-5-13-25/h8-11,16H,2-7,12-15H2,1H3Purity: ≥98% (or refer to the Certificate…

Propargyl-PEG1-SS-alcohol

Product Name : Propargyl-PEG1-SS-alcoholDescription:Propargyl-PEG1-SS-alcohol is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).CAS: 1391914-41-2Molecular Weight:192.30Formula: C7H12O2S2Chemical Name: 2-{disulfanyl}ethan-1-olSmiles : C#CCOCCSSCCOInChiKey: WFZUBJGVOIBKLI-UHFFFAOYSA-NInChi : InChI=1S/C7H12O2S2/c1-2-4-9-5-7-11-10-6-3-8/h1,8H,3-7H2Purity:…

HO-PEG13-OH

Product Name : HO-PEG13-OHDescription:HO-PEG13-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.CAS: 17598-96-8Molecular Weight:590.70Formula: C26H54O14Chemical Name: 3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxaoctatriacontane-1,38-diolSmiles : OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOInChiKey: AKWFJQNBHYVIPY-UHFFFAOYSA-NInChi : InChI=1S/C26H54O14/c27-1-3-29-5-7-31-9-11-33-13-15-35-17-19-37-21-23-39-25-26-40-24-22-38-20-18-36-16-14-34-12-10-32-8-6-30-4-2-28/h27-28H,1-26H2Purity: ≥98% (or…

Gly-PEG3-endo-BCN

Product Name : Gly-PEG3-endo-BCNDescription:Gly-PEG3-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.CAS: 2354291-37-3Molecular Weight:453.57Formula: C23H39N3O6Chemical Name: non-4-yn-9-yl]methyl N-ethoxy}ethoxy)propyl]carbamateSmiles : NCC(=O)NCCCOCCOCCOCCCNC(=O)OCC12CCC#CCC21InChiKey: MZZHRBCWKALCAE-WCRBZPEASA-NInChi : InChI=1S/C23H39N3O6/c24-17-22(27)25-9-5-11-29-13-15-31-16-14-30-12-6-10-26-23(28)32-18-21-19-7-3-1-2-4-8-20(19)21/h19-21H,3-18,24H2,(H,25,27)(H,26,28)/t19-,20+,21?Purity: ≥98%…

Ald-Ph-amido-PEG11-NH-Boc

Product Name : Ald-Ph-amido-PEG11-NH-BocDescription:Ald-Ph-amido-PEG11-NH-Boc is a non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).CAS: 1245813-70-0Molecular Weight:776.91Formula: C37H64N2O15Chemical Name: tert-butyl N-{35--3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontan-1-yl}carbamateSmiles : CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)C1C=CC(=CC=1)C=OInChiKey: RDSLXILMKJRJBU-UHFFFAOYSA-NInChi :…

Glucosinalbate potassium

Product Name : Glucosinalbate potassiumDescription:Glucosinalbate potassium is a natural product that can be isolated from Arabidopsis thaliana.CAS: 16411-05-5Molecular Weight:463.52Formula: C14H18KNO10S2Chemical Name: potassium (Z)-sulfanyl}ethylidene]amino sulfateSmiles : .S(=O)(=O)O/N=C(/CC1=CC=C(O)C=C1)\S1O(CO)(O)(O)1OInChiKey: LAMNAIMKLRHPRP-UDQIAKBUSA-MInChi : InChI=1S/C14H19NO10S2.K/c16-6-9-11(18)12(19)13(20)14(24-9)26-10(15-25-27(21,22)23)5-7-1-3-8(17)4-2-7;/h1-4,9,11-14,16-20H,5-6H2,(H,21,22,23);/q;+1/p-1/b15-10-;/t9-,11-,12+,13-,14+;/m1./s1Purity: ≥98%…

6-Hydroxy-4-methylcoumarin

Product Name : 6-Hydroxy-4-methylcoumarinDescription:6-Hydroxy-4-methylcoumarin (compound 9) is a coumarins secondary metabolites and has anticancer activity.CAS: 2373-31-1Molecular Weight:176.17Formula: C10H8O3Chemical Name: 6-hydroxy-4-methyl-2H-chromen-2-oneSmiles : CC1=CC(=O)OC2=CC=C(O)C=C21InChiKey: IRUHWRSITUYICV-UHFFFAOYSA-NInChi : InChI=1S/C10H8O3/c1-6-4-10(12)13-9-3-2-7(11)5-8(6)9/h2-5,11H,1H3Purity: ≥98% (or refer to the…

4-Hydroxyestrone-d4

Product Name : 4-Hydroxyestrone-d4Description:Product informationCAS: 81586-98-3Molecular Weight:290.39Formula: C18H22O3Chemical Name: (3aS,3bR,9bS,11aS)-6,7-dihydroxy-11a-methyl(2,2,8,9-²H₄)-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopentaphenanthren-1-oneSmiles : C1()C23CCC4=C(3CC2(C)C1=O)C()=C()C(O)=C4OInChiKey: XQZVQQZZOVBNLU-RFZGAVBWSA-NInChi : InChI=1S/C18H22O3/c1-18-9-8-11-10-4-6-15(19)17(21)13(10)3-2-12(11)14(18)5-7-16(18)20/h4,6,11-12,14,19,21H,2-3,5,7-9H2,1H3/t11-,12-,14+,18+/m1/s1/i4D,6D,7D2Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous…

nTZDpa

Product Name : nTZDpaDescription:Product informationCAS: 118414-59-8Molecular Weight:428.33Formula: C22H15Cl2NO2SChemical Name: 5-chloro-1--3-(phenylsulfanyl)-1H-indole-2-carboxylic acidSmiles : OC(=O)C1=C(SC2C=CC=CC=2)C2=CC(Cl)=CC=C2N1CC1C=CC(Cl)=CC=1InChiKey: VUPOTURDKDMIGQ-UHFFFAOYSA-NInChi : InChI=1S/C22H15Cl2NO2S/c23-15-8-6-14(7-9-15)13-25-19-11-10-16(24)12-18(19)21(20(25)22(26)27)28-17-4-2-1-3-5-17/h1-12H,13H2,(H,26,27)Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as…

N20C hydrochloride

Product Name : N20C hydrochlorideDescription:Product informationCAS: 1177583-87-7Molecular Weight:304.81Formula: C17H21ClN2OChemical Name: 2-acetamide hydrochlorideSmiles : Cl.NC(=O)CNCCC(C1C=CC=CC=1)C1C=CC=CC=1InChiKey: JCJDLPUASJEVRN-UHFFFAOYSA-NInChi : InChI=1S/C17H20N2O.ClH/c18-17(20)13-19-12-11-16(14-7-3-1-4-8-14)15-9-5-2-6-10-15;/h1-10,16,19H,11-13H2,(H2,18,20);1HPurity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature…

Aminoglutethimide

Product Name : AminoglutethimideDescription:Aminoglutethimide is an aromatase inhibitor with IC50 of 10 μM.CAS: 125-84-8Molecular Weight:232.28Formula: C13H16N2O2Chemical Name: 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dioneSmiles : CCC1(CCC(=O)NC1=O)C1C=CC(N)=CC=1InChiKey: ROBVIMPUHSLWNV-UHFFFAOYSA-NInChi : InChI=1S/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-6H,2,7-8,14H2,1H3,(H,15,16,17)Purity: ≥98% (or refer to the Certificate of…

5′-O-(tert-Butyldimethylsilyl)thymidine, 97+%

Product Name : 5'-O-(tert-Butyldimethylsilyl)thymidine, 97+%Synonym: IUPAC Name : 1-methyl}-4-hydroxyoxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dioneCAS NO.:40733-28-6Molecular Weight : Molecular formula: C16H28N2O5SiSmiles: CC1=CN(2C(O)(CO(C)(C)C(C)(C)C)O2)C(=O)NC1=ODescription: 5'-O-(tert-Butyldimethylsilyl)thymidine is used as pharmaceutical intermediate.S1p receptor agonist 1 Ganciclovir PMID:24633055 MedChemExpress (MCE) offers…

Sisomicin sulfate, 90%

Product Name : Sisomicin sulfate, 90%Synonym: IUPAC Name : (2R,3R,4R,5R)-2-{oxy}-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol; sulfuric acidCAS NO.Hoechst 33342 :53179-09-2Molecular Weight : Molecular formula: C19H39N5O11SSmiles: OS(O)(=O)=O.Pozelimab CN1(O)(O2(N)C(N)(O3OC(CN)=CC3N)2O)OC1(C)ODescription: PMID:23008002 MedChemExpress (MCE) offers a wide range of…

Fexofenadine hydrochloride

Product Name : Fexofenadine hydrochlorideSynonym: IUPAC Name : hydrogen 2-(4-{1-hydroxy-4-butyl}phenyl)-2-methylpropanoic acid chlorideCAS NO.:153439-40-8Molecular Weight : Molecular formula: C32H40ClNO4Smiles: .Biotin Hydrazide .Ferritin heavy chain/FTH1 Protein, Human CC(C)(C(O)=O)C1=CC=C(C=C1)C(O)CCCN1CCC(CC1)C(O)(C1=CC=CC=C1)C1=CC=CC=C1Description: Fexofenadine hydrochloride is used…

: 5GCTGATGCCAATGACGATGA-3 for ABCG8; forward: 5-CCGTGGCTTTTTCTTCTCTCA-3 and reverse: 5GCATTCGGAACAGTGCAACA-3; for SCD-1; forward

: 5GCTGATGCCAATGACGATGA-3 for ABCG8; forward: 5-CCGTGGCTTTTTCTTCTCTCA-3 and reverse: 5GCATTCGGAACAGTGCAACA-3; for SCD-1; forward: 5-CACCCCCTCGTTGAAAACCT-3 and reverse: 5CCTTAGCCAGCTCTTCCAGATC-3 for LDLR; forward: 5-GCATTCGGAACAGTGCAACA-3 and reverse: 5TCATGAATGGTGCCCACATC-3 for SR-B1; and forward: 5-GAAGACACCAGTAGACTCCACGACATA-3 and reverse:…

.K.,.K. Conflict of Interest: Noconflictofinterestwasdeclaredbytheauthors. Financial Disclosure: The authors declared

.K.,.K. Conflict of Interest: Noconflictofinterestwasdeclaredbytheauthors. Monetary Disclosure: The authors declared that this study has received no financialsupport.magnesium levels of two.53.5 mg/dL in comparison with the controlgroup(thisroughlycorrelatesto1.04.21mmol/Lwhen convertedtoSIunitusingtheconversionfactor0.4114).Interestingly, they didn't use…

SofthenormalizedFdvaluesexhibitedasingle- eak p curveforP. tabulaeformis,whileH. rhamnoidesexhibitedamultipeakcurve just before andafter rainfall (Figures

SofthenormalizedFdvaluesexhibitedasingle- eak p curveforP. tabulaeformis,whileH. rhamnoidesexhibitedamultipeakcurve ahead of andafter rainfall (Figures4a,b). ThenormalizedFd values had been approximately zero in between 0:00 and 6:00hr, and it increasedshortlyaftersunrise.ThenormalizedFdvaluesdecreasedtoa relativelylowerlevelaftersunsetandgraduallyreachedtheminimum aftermidnight.ThediurnalcoursesofthenormalizedFdforP. tabulaeformisremainedrelativelystablebeforeandafterrainfalleventsinthe 3 periods…

Bp1-/Trif-/WT 7 11 24 0 16 12 0 14 27Genotype of offspring Genotype of parentsTrifwt-/Ripk

Bp1-/Trif-/WT 7 11 24 0 16 12 0 14 27Genotype of offspring Genotype of parentsTrifwt-/Ripk1mRHIM/mRHIMWTNature. Author manuscript; readily available in PMC 2018 January 05.Ripk1mRHIM/wt Ripk1mRHIM/wt Ripk1mRHIM/mRHIM0LineRipk1wt/mRHIMTrifwt/Ripk1wt/mRHIMTrifwt-/-Ripk1wt/mRHIMTrifwt/Ripk1wt/mRHIMTrif-/-Europe PMC Funders Author ManuscriptsPageEurope…

G. 2, 2-chloropodophyllotoxin (four), 2,6-dichloropodophyllotoxin (5), and 2-bromopodophyllotoxin (6) had been firstly Angiopoietin-2 Protein MedChemExpress

G. 2, 2-chloropodophyllotoxin (four), 2,6-dichloropodophyllotoxin (5), and 2-bromopodophyllotoxin (6) had been firstly Angiopoietin-2 Protein MedChemExpress obtained as described previouslyG. two, 2-chloropodophyllotoxin (4), two,6-dichloropodophyllotoxin (five), and 2-bromopodophyllotoxin (6) have been firstly…