Tality in patients with severe sepsis/septic shock as defined by international get GSK189254A criteria.SCritical CareMarch 2007 Vol 11 Suppl27th International Symposium on Intensive Care and Emergency MedicineMethods A prospective observational study was performed on patients admitted to a general adult ICU within 24 hours of the development of severe sepsis/septic shock. Serial TnT samples were taken over the first 96 hours. Patients were grouped into three groups: A, TnT < 0.01 ng/ml; B, TnT 0.01?.099 ng/ml; and C, TnT > 0.099 ng/ml. Results Blood from 49 patients was analysed. The peak Troponin level was elevated (>0.01 ng/ml) in 39/49 patients (80 ). There was no significant difference between the three groups in terms of hypertension, history of angina, myocardial infarction or systolic blood pressure at time of ICU admission. Patients with undetectable TnT levels (<0.01 g/ml) had significantly lower 6month mortality rates than those with detectable levels (group A 2/10 (20 ) vs Group B/C 23/39 (59 ), P = 0.037; group B 8/15 (53 ), group C 15/24 (63 )). See Table 1.Table 1 (abstract P239) Group A B C Number 10 15 24 APACHE II Mean score age (years) 18.5 (8.2) 20 (5.7) 22.2 (6.8) 52 (17) 63 (15) 65 (14) Inotropic support 8 15 22 Mortality 2/10 8/15 15/(odds ratio 1.29 for 1,000 units) and no administration of inotropic drug on day 1 (odds ratio 34.5) decrease the probability of inhospital complications. The average efficacy of prognostication reached 96.5 ; the presence of complications was correctly predicted in 88.9 of cases, and the absence of complications in 100 of cases. Conclusion The HRV parameter LF on day 3, and LV ESV, atrial fibrillation/flutter and inotropic agent administration on day 1 are statistically significant independent predictors of inhospital complications of MI with an average predictive efficacy of 96.5 .P241 The relationship between blood pressure and plasma magnesium level in hypertensive patientsA Bayir, B Cander, A Ak, S Girisgin University, Meram Faculty of Medicine, Konya, Turkey Critical Care 2007, 11(Suppl 2):P241 (doi: 10.1186/cc5401) Introduction The aim of this study was to investigate the relationship between blood pressure and plasma magnesium levels in patients referred to the emergency department with hypertensive attack. Epidemiological evidence on the effects of magnesium on blood pressure is inconsistent. Metabolic and experimental studies suggest that magnesium may have a role in the regulation of blood pressure. Magnesium regulates various ion channels in many tissues, including those of the cardiovascular system. Magnesium is the second most abundant intracellular cation, and the important element that has numerous biological functions in the cardiovascular system. Furthermore, magnesium acts as a calcium antagonist, regulating the calcium metabolism. Methods Patients were included who were taken to PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20740215 the emergency department due to hypertensive attack. Their age, gender, systolic and diastolic blood pressure were recorded. In order to see the plasma magnesium levels, venous blood samples were taken. The results were compared with a chi-square test. The values P < 0.05 were accepted as significant. Results Seventy-three patients (35 of whom were female, 38 males) were included in the study. The average age was 47 ?6.3 (ranging from 33 to 68 years). The average blood pressure of the patients was found as systolic 200 ?10 (range 185?40) mmHg, diastolic 105 ?7 (range 95?10) mmHg. The average plasma magne.