T damaged-based groupings of the six VercirnonMedChemExpress GSK-1605786 different wards that form central Christchurch. In doing so, we examined the possibility that levels of psychological distress may have decreased for some regions, but not others (i.e, those regions that suffered the most property damage). On a positive note the mean total K6 scores across regions indicate a fairly low level of psychological distress in the population of central Christchurch. Indeed, the K6 is a DSM-IV diagnostic tool and, as such, is designed to screen for serious/clinical levels of mental distress [29, 36,37]. Because it is unlikely that a natural disaster would lead substantial portions of a population to develop a serious mental disorder, the relatively low mean levels of psychological distress reported in the current study are unsurprising.The least-damaged regionOur findings do, however, indicate that there are differential rates of psychological Vorapaxar dose recovery among people living in the different regions of central Christchurch. These results corroboratePLOS ONE | DOI:10.1371/journal.pone.0124278 May 1,7 /Regional Differences in Psychological Recoveryprevious research showing that those in the regions of Christchurch with the least amount of property damage reported the lowest levels of psychological distress [26]. Where we diverge from this earlier research is that we show that differences in recovery rates emerge years down the track [26]. Indeed, the two most damaged ward-groupings had fairly stable K6 scores over the time period, whereas the least damaged region (i.e., Fendalton-Waimairi and Riccarton Wigram) experienced a considerable drop in psychological distress in 2012. This suggests that the participants in the least-damaged region had some level of psychological recovery. Although we do not know the participant’s pre-earthquake K6 scores, our results show a decrease in scores in 2012 since the initial data collection, that is, around the time of the first big earthquakes, and following data collection in 2011, the year after the earthquakes.The moderately-damaged and most-damaged regionsIn late 2012, the level of psychological distress reported by those who had lived (or were continuing to live) in the moderately-damaged wards of Hagley-Ferrymead and Spreydon-Heathcote was significantly higher than the levels of psychological distress reported by those who had lived (or were continuing to live) in the (least-damaged) region covered by the RiccartonWigram and Fendalton-Waimairi wards. In other words, participants living in the moderatelydamaged regions of Christchurch failed to experience a drop in psychological distress nearly three years after the two major earthquakes that struck the Canterbury region. Although we hypothesised that those from the moderately-damaged region would show some level of psychological recovery, they did not. One plausible reason for the lack of recovery among those living in this region may be that the earthquakes also altered the geology of the Heathcote River (which runs through the Spreydon-Heathcote ward). As such, residents were subjected to increased risks of flooding following the earthquakes [38]. Indeed, the Heathcote River has `burst its banks’ many times over the last couple of years following the two major earthquakes, which has resulted in further damage–especially in light of the earthquake-damaged drainage system–and additional insurance claims for its residents. This may have slowed psychological recovery in this region. It is.T damaged-based groupings of the six different wards that form central Christchurch. In doing so, we examined the possibility that levels of psychological distress may have decreased for some regions, but not others (i.e, those regions that suffered the most property damage). On a positive note the mean total K6 scores across regions indicate a fairly low level of psychological distress in the population of central Christchurch. Indeed, the K6 is a DSM-IV diagnostic tool and, as such, is designed to screen for serious/clinical levels of mental distress [29, 36,37]. Because it is unlikely that a natural disaster would lead substantial portions of a population to develop a serious mental disorder, the relatively low mean levels of psychological distress reported in the current study are unsurprising.The least-damaged regionOur findings do, however, indicate that there are differential rates of psychological recovery among people living in the different regions of central Christchurch. These results corroboratePLOS ONE | DOI:10.1371/journal.pone.0124278 May 1,7 /Regional Differences in Psychological Recoveryprevious research showing that those in the regions of Christchurch with the least amount of property damage reported the lowest levels of psychological distress [26]. Where we diverge from this earlier research is that we show that differences in recovery rates emerge years down the track [26]. Indeed, the two most damaged ward-groupings had fairly stable K6 scores over the time period, whereas the least damaged region (i.e., Fendalton-Waimairi and Riccarton Wigram) experienced a considerable drop in psychological distress in 2012. This suggests that the participants in the least-damaged region had some level of psychological recovery. Although we do not know the participant’s pre-earthquake K6 scores, our results show a decrease in scores in 2012 since the initial data collection, that is, around the time of the first big earthquakes, and following data collection in 2011, the year after the earthquakes.The moderately-damaged and most-damaged regionsIn late 2012, the level of psychological distress reported by those who had lived (or were continuing to live) in the moderately-damaged wards of Hagley-Ferrymead and Spreydon-Heathcote was significantly higher than the levels of psychological distress reported by those who had lived (or were continuing to live) in the (least-damaged) region covered by the RiccartonWigram and Fendalton-Waimairi wards. In other words, participants living in the moderatelydamaged regions of Christchurch failed to experience a drop in psychological distress nearly three years after the two major earthquakes that struck the Canterbury region. Although we hypothesised that those from the moderately-damaged region would show some level of psychological recovery, they did not. One plausible reason for the lack of recovery among those living in this region may be that the earthquakes also altered the geology of the Heathcote River (which runs through the Spreydon-Heathcote ward). As such, residents were subjected to increased risks of flooding following the earthquakes [38]. Indeed, the Heathcote River has `burst its banks’ many times over the last couple of years following the two major earthquakes, which has resulted in further damage–especially in light of the earthquake-damaged drainage system–and additional insurance claims for its residents. This may have slowed psychological recovery in this region. It is.