Name :
IL18BP (Human) Recombinant protein
Biological Activity :
Human IL18BP (O95998, 31 a.a. – 194 a.a) partial recombinant protein with His-tag at N-terminal expressed in Escherichia Coli.
Tag :
Protein Accession No. :
O95998
Protein Accession No.URL :
https://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=10068
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSTPVSQTT TAATASVRST KDPCPSQPPV FPAAKQCPAL EVTWPEVEVP LNGTLSLSCV ACSRFPNFSI LYWLGNGSFI EHLPGRLWEG STSRERGSTG TQLCKALVLE QLTPALHSTN FSCVLVDPEQ VVQRHVVLAQ LWAGLRATLP PTQEALPSSH SSPQQQG.
Molecular Weight :
20
Storage and Stability :
Store at 4°C for 2~4 week. For long term storage store at -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Aliquot to avoid repeated freezing and thawing.
Host :
Escherichia coli
Interspecies Antigen Sequence :
Preparation Method :
Escherichia coli expression system
Purification :
Quality Control Testing :
Storage Buffer :
In 20mM Tris-HCl buffer, pH 8.0, 0.4M UREA and 10% glycerol.
Applications :
SDS-PAGE，
Gene Name :
IL18BP
Gene Alias :
IL18BPa
Gene Description :
interleukin 18 binding protein
Gene Summary :
The protein encoded by this gene is an inhibitor of the proinflammatory cytokine IL18. This protein binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. This protein is constitutively expressed and secreted in mononuclear cells. The expression of this protein can be enhanced by IFN-gamma. An elevated level of this protein is detected in the intestinal tissues of patients with Crohn’s disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations :
MC51L-53L-54L homolog gene product|OTTHUMP00000179141|OTTHUMP00000179143
MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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