Product Name :
1′-Hydroxymidazolam
Description:
1′-Hydroxymidazolam is a primary active metabolite of Midazolam, and it is a neuronal depressant agent. 1′-Hydroxymidazolam could inhibit neuronal activity add to the effects of Midazolam.
CAS:
59468-90-5
Molecular Weight:
341.77
Formula:
C18H13ClFN3O
Chemical Name:
[12-chloro-9-(2-fluorophenyl)-2,4,8-triazatricyclo[8.4.0.0²,⁶]tetradeca-1(14),3,5,8,10,12-hexaen-3-yl]methanol
Smiles :
OCC1=NC=C2CN=C(C3=CC(Cl)=CC=C3N12)C1=CC=CC=C1F
InChiKey:
QHSMEGADRFZVNE-UHFFFAOYSA-N
InChi :
InChI=1S/C18H13ClFN3O/c19-11-5-6-16-14(7-11)18(13-3-1-2-4-15(13)20)22-9-12-8-21-17(10-24)23(12)16/h1-8,24H,9-10H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
1′-Hydroxymidazolam is a primary active metabolite of Midazolam, and it is a neuronal depressant agent. 1′-Hydroxymidazolam could inhibit neuronal activity add to the effects of Midazolam.|Product information|CAS Number: 59468-90-5|Molecular Weight: 341.77|Formula: C18H13ClFN3O|Chemical Name: [12-chloro-9-(2-fluorophenyl)-2,4,8-triazatricyclo[8.4.0.0²,⁶]tetradeca-1(14),3,5,8,10,12-hexaen-3-yl]methanol|Smiles: OCC1=NC=C2CN=C(C3=CC(Cl)=CC=C3N12)C1=CC=CC=C1F|InChiKey: QHSMEGADRFZVNE-UHFFFAOYSA-N|InChi: InChI=1S/C18H13ClFN3O/c19-11-5-6-16-14(7-11)18(13-3-1-2-4-15(13)20)22-9-12-8-21-17(10-24)23(12)16/h1-8,24H,9-10H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{TAT peptide} web|{TAT peptide} Anti-infection|{TAT peptide} Technical Information|{TAT peptide} References|{TAT peptide} manufacturer|{TAT peptide} Cancer} |Shelf Life: ≥12 months if stored properly.{{Vilobelimab} MedChemExpress|{Vilobelimab} SARS-CoV|{Vilobelimab} Technical Information|{Vilobelimab} References|{Vilobelimab} supplier|{Vilobelimab} Epigenetic Reader Domain} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23916866 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|1′-Hydroxymidazolam (5 nM-1 µM) induces a significant inhibition of the action potential firing rate at concentrations of 100 nM or higher and causes a steady increase in the depression of network activity with increasing concentrations of up to 1 µM in neocortical slice cultures from wild-type mice.|Products are for research use only. Not for human use.|